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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

    IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

    IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

ARAP3 Polyclonal antibody, PBS Only

ARAP3 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 22578-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

22578-1-PBS targets ARAP3 in IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 ARAP3 fusion protein Ag17436 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
别名
计算分子量 1544 aa, 170 kDa
GenBank蛋白编号BC009968
基因名称 ARAP3
Gene ID (NCBI) 64411
RRIDAB_2879125
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8WWN8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ARAP3 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3) is unique for its dual specificity GAPs (GTPase activating protein) activity for Arf6 (ADP-ribosylation factor 6) and RhoA (Ras homolog gene family member A) regulated by PtdIns(3,4,5)P3 (phosphatidylinositol (3,4,5)-trisphosphate) and a small GTPase Rap1-GTP and is involved in regulation of cell shape and adhesion.