• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85089-1-RR (same clone as 85089-1-PBS)

    WB analysis using 85089-1-RR (same clone as 85089-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85089-1-RR (ASIC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85089-1-PBS in a different storage buffer formulation.

  • WB analysis using 85089-1-RR (same clone as 85089-1-PBS)

    WB analysis using 85089-1-RR (same clone as 85089-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85089-1-RR (ASIC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85089-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01789-2

    Cytometric bead array standard curve of MP01789-2

    Cytometric bead array standard curve of MP01789-2, ASIC1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85089-1-PBS. Detection antibody: 85089-2-PBS. Standard: Ag25941. Range: 0.313-40 ng/mL.

  • Cytometric bead array standard curve of MP01789-1

    Cytometric bead array standard curve of MP01789-1

    Cytometric bead array standard curve of MP01789-1, ASIC1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85089-1-PBS. Detection antibody: 85089-3-PBS. Standard: Ag25941. Range: 0.313-40 ng/mL.

ASIC1 Recombinant antibody, PBS Only (Capture)

ASIC1 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 85089-1-PBS

Print datasheet

CloneNo. 242749B11

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Synonyms

ACCN2, ASIC, Amiloride-sensitive cation channel 2, neuronal, Acid-sensing ion channel 1, 242749B11

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

85089-1-PBS targets ASIC1 as part of a matched antibody pair:

MP01789-1: 85089-1-PBS capture and 85089-3-PBS detection (validated in Cytometric bead array)

MP01789-2: 85089-1-PBS capture and 85089-2-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen ASIC1 fusion protein Ag25941 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name amiloride-sensitive cation channel 2, neuronal
Synonyms ACCN2, ASIC, Amiloride-sensitive cation channel 2, neuronal, Acid-sensing ion channel 1, 242749B11
Calculated Molecular Weight 60 kDa
Observed Molecular Weight60-70 kDa
GenBank Accession NumberNM_001095
Gene Symbol ASIC1
Gene ID (NCBI) 41
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP78348
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ASIC1(Acid-sensing ion channel 1), also named as ACCN2, BNaC2 or amiloride-sensitive cation channel 2, is a member of the ASICs family. ASICs, an H+-gated subgroup of the epithelial Na+ channel/degenerin (ENaC/DEG) superfamily, are widely expressed throughout the central and peripheral nervous system and triggered by increased extracellular acidification (PMID: 28518134, 27941930). ASIC1 is a key player in acidosis-induced tumor growth and invasiveness. Clinically, alterations of ASIC1 are associated with poor survival in breast cancer (PMID: 26686084).