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  • Featured Product
  • KD/KO Validated

Beta Arrestin 1 Monoclonal antibody, PBS Only

Beta Arrestin 1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H8E4

Cat no : 67580-1-PBS

Print datasheet

Synonyms

ARRB1, ARR1, ARR 1, ARB2, ARB1

验证数据展示

  • WB analysis using 67580-1-Ig (same clone as 67580-1-PBS)

    WB analysis using 67580-1-Ig (same clone as 67580-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 67580-1-Ig (same clone as 67580-1-PBS)

    IHC staining of mouse brain using 67580-1-Ig (same clone as 67580-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67580-1-Ig (Beta Arrestin 1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with ARRB1 antibody included
  • WB analysis of HepG2 using 67580-1-Ig (same clone as 67580-1-PBS)

    WB analysis of HepG2 using 67580-1-Ig (same clone as 67580-1-PBS)

    WB result of Beta Arrestin 1 antibody (67580-1-Ig; 1:8000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Beta Arrestin 1 transfected HepG2 cells. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy ARRB1 Ready-To-Use IHC Kit. ARRB1 primary antibody included.

产品信息

67580-1-PBS targets Beta Arrestin 1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Beta Arrestin 1 fusion protein Ag7504 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name arrestin, beta 1
Synonyms ARRB1, ARR1, ARR 1, ARB2, ARB1
Calculated Molecular Weight 47 kDa
Observed Molecular Weight 45-55 kDa
GenBank Accession NumberBC003636
Gene Symbol Beta Arrestin 1
Gene ID (NCBI) 408
RRIDAB_2882791
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP49407
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).