验证数据展示
经过测试的应用
Positive FC detected in | human peripheral blood leukocytes |
推荐稀释比
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
98226-1-RR targets C5AR1/CD88 in FC applications and shows reactivity with human samples.
Tested Applications | FC Application Description |
Tested Reactivity | human |
Immunogen | Recombinant protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | complement component 5a receptor 1 |
Synonyms | C5AR, C5AR1, C5a-R, C5a R, C5a anaphylatoxin chemotactic receptor 1 |
Calculated Molecular Weight | 39kDa |
GenBank Accession Number | NM_001736.4 |
Gene Symbol | C5aR |
Gene ID (NCBI) | 728 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P21730 |
Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
背景介绍
C5aR, also named CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release, and superoxide anion production.
实验方案
Product Specific Protocols | |
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FC protocol for C5AR1/CD88 antibody 98226-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |