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Species Reactivity
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Conjugate
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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98226-1-RR

    FC experiment of human peripheral blood leukocytes using 98226-1-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human C5AR1/CD88 Rabbit Recombinant Antibody (98226-1-RR, Clone: 241712D4) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD16. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • FC experiment of human peripheral blood leukocytes using 98226-1-RR

    FC experiment of human peripheral blood leukocytes using 98226-1-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human C5AR1/CD88 Rabbit Recombinant Antibody (98226-1-RR, Clone: 241712D4) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • Affinity and Kinetic Characterization of 98226-1-RR

    Affinity and Kinetic Characterization of 98226-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98226-1-RR against Human C5AR1/CD88 were performed. The affinity constant is 1.56 nM.

Anti-Human C5AR1/CD88 Rabbit Recombinant Antibody

C5AR1/CD88 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98226-1-RR

产品说明书

CloneNo. 241712D4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

C5AR, C5AR1, 241712D4, C5A, C5a anaphylatoxin chemotactic receptor 1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive FC detected inhuman peripheral blood leukocytes
Planning an IHC experiment? We recommend our IHCeasy C5AR1 Ready-To-Use IHC Kit. C5AR1 primary antibody included.

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98226-1-RR targets C5AR1/CD88 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 complement component 5a receptor 1
别名 C5AR, C5AR1, 241712D4, C5A, C5a anaphylatoxin chemotactic receptor 1
计算分子量39kDa
GenBank蛋白编号NM_001736.4
基因名称 C5aR
Gene ID (NCBI) 728
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP21730
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

C5aR, also named CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release, and superoxide anion production.

实验方案

Product Specific Protocols
FC protocol for C5AR1/CD88 antibody 98226-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols