验证数据展示
产品信息
98226-1-PBS targets C5AR1/CD88 in FC applications and shows reactivity with human samples.
Tested Applications | FC Application Description |
Tested Reactivity | human |
Immunogen | Recombinant protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | complement component 5a receptor 1 |
Synonyms | C5AR, C5AR1, C5a-R, C5a R, C5a anaphylatoxin chemotactic receptor 1 |
Calculated Molecular Weight | 39kDa |
GenBank Accession Number | NM_001736.4 |
Gene Symbol | C5aR |
Gene ID (NCBI) | 728 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P21730 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
C5aR, also named CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release, and superoxide anion production.