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CAMK4 Monoclonal antibody, PBS Only

CAMK4 Monoclonal Antibody for WB,Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G7A7

Cat No : 68452-1-PBS

Print datasheet

Synonyms

CaM kinase GR, CaMK GR, CaMK IV, CAMK4

验证数据展示

  • WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68452-1-Ig (CAMK4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68452-1-PBS in a different storage buffer formulation.

产品信息

68452-1-PBS targets CAMK4 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Applications WB,Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat
Immunogen CAMK4 fusion protein Ag33332 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name calcium/calmodulin-dependent protein kinase IV
Synonyms CaM kinase GR, CaMK GR, CaMK IV, CAMK4
Calculated Molecular Weight 473 aa, 52 kDa
Observed Molecular Weight56-65 kDa
GenBank Accession NumberBC025687
Gene Symbol CAMK4
Gene ID (NCBI) 814
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ16566
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

CaMK4 (Calcium/calmodulin-dependent protein kinase IV) is a multifunctional serine/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225)