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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68452-1-Ig (CAMK4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68452-1-PBS in a different storage buffer formulation.

CAMK4 Monoclonal antibody, PBS Only

CAMK4 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68452-1-PBS

产品说明书

CloneNo. 1G7A7

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, rat

应用

WB, Indirect ELISA

别名

CaM kinase GR, CaMK GR, CaMK IV, CAMK4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68452-1-PBS targets CAMK4 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 CAMK4 fusion protein Ag33332 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 calcium/calmodulin-dependent protein kinase IV
别名 CaM kinase GR, CaMK GR, CaMK IV, CAMK4
计算分子量 473 aa, 52 kDa
观测分子量56-65 kDa
GenBank蛋白编号BC025687
基因名称 CAMK4
Gene ID (NCBI) 814
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ16566
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CaMK4 (Calcium/calmodulin-dependent protein kinase IV) is a multifunctional serine/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225)