CoraLite® Plus 488-conjugated CAPNS1 Monoclonal antibody
CAPNS1 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
Human, rat
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2B6G6
验证数据展示
经过测试的应用
Positive IF detected in | A431 cells |
Planning an IHC experiment? We recommend our IHCeasy CAPNS1 Ready-To-Use IHC Kit. CAPNS1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67838-1-Ig
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-67838 targets CAPNS1 in IF applications and shows reactivity with Human, rat samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | Human, rat |
Immunogen | CAPNS1 fusion protein Ag21885 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | calpain, small subunit 1 |
Synonyms | 30K, Calpain regulatory subunit, Calpain small subunit 1, calpain, small subunit 1, CALPAIN4, CANP, CANP small subunit, CANPS, CAPN4, CAPNS, CAPNS1, CDPS, CSS1 |
Calculated Molecular Weight | 28 kDa |
GenBank Accession Number | BC011903 |
Gene Symbol | CAPNS1 |
Gene ID (NCBI) | 826 |
RRID | AB_2919558 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P04632 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CAPNS1 is also named as CANP, CDPS, CSS1, CANPS, CAPN4 and CALPAIN4. It is a member of the calpain small subunit family, and belongs to the calcium-dependent family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. The small regulatory subunit consists of an N-terminal domain, containing about 30% glycine residues and a C-terminal Ca-binding domain (PMID: 9228946). This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy.
实验方案
Product Specific Protocols | |
---|---|
IF protocol for CL Plus 488 CAPNS1 antibody CL488-67838 | Download protocol |
FC protocol for CL Plus 488 CAPNS1 antibody CL488-67838 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |