验证数据展示
经过测试的应用
Positive FC detected in | mouse splenocytes |
推荐稀释比
应用 | 推荐稀释比 |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
IF | See 2 publications below |
FC | See 1 publications below |
产品信息
65047-1-Ig targets CD103 in IF, FC applications and shows reactivity with Mouse samples.
经测试应用 | FC Application Description |
文献引用应用 | IF, FC |
经测试反应性 | Mouse |
文献引用反应性 | mouse |
免疫原 | C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) 种属同源性预测 |
宿主/亚型 | Hamster / IgG |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | integrin alpha E, epithelial-associated |
别名 | A530055J10, alpha E1, alpha M290, aM290, CD103, Integrin alpha E, Integrin alpha M290, Itgae |
GenBank蛋白编号 | BC150690 |
基因名称 | CD103 |
Gene ID (NCBI) | 16407 |
RRID | AB_2918359 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Affinity purification |
UNIPROT ID | Q60677 |
储存缓冲液 | PBS with 0.09% sodium azide , pH 7.3 |
储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).
实验方案
Product Specific Protocols | |
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FC protocol for CD103 antibody 65047-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
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Biomolecules Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice | ||
J Nanobiotechnology Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair | ||
Biomed Pharmacother Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice |