Anti-Mouse CD103 (2E7)
CD103 Monoclonal Antibody for FC
Host / Isotype
Hamster / IgG
Reactivity
Mouse and More (1)
Applications
FC and More (1)
Conjugate
Unconjugated
CloneNo.
2E7
验证数据展示
经过测试的应用
Positive FC detected in | mouse splenocytes |
推荐稀释比
Application | Dilution |
---|---|
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
IF | See 2 publications below |
FC | See 1 publications below |
产品信息
65047-1-Ig targets CD103 in IF, FC applications and shows reactivity with Mouse samples.
Tested Applications | FC Application Description |
Cited Applications | IF, FC |
Tested Reactivity | Mouse |
Cited Reactivity | mouse |
Immunogen | C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) 种属同源性预测 |
Host / Isotype | Hamster / IgG |
Class | Monoclonal |
Type | Antibody |
Full Name | integrin alpha E, epithelial-associated |
Synonyms | A530055J10, alpha E1, alpha M290, aM290, CD103, Integrin alpha E, Integrin alpha M290, Itgae |
GenBank Accession Number | BC150690 |
Gene Symbol | CD103 |
Gene ID (NCBI) | 16407 |
RRID | AB_2918359 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
UNIPROT ID | Q60677 |
Storage Buffer | PBS with 0.09% sodium azide. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).
实验方案
Product Specific Protocols | |
---|---|
FC protocol for CD103 antibody 65047-1-Ig | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Biomolecules Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice | ||
J Nanobiotechnology Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair | ||
Biomed Pharmacother Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice |