CoraLite® Plus 647 Anti-Mouse CD103 (2E7)

CD103 Monoclonal Antibody for FC

Host / Isotype

Hamster / IgG

Reactivity

Mouse

Applications

FC

Conjugate

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

2E7

Cat no : CL647-65047

Print datasheet

Synonyms

A530055J10, alpha E1, alpha M290, aM290, CD103, Integrin alpha E, Itgae



经过测试的应用

Positive FC detected inmouse splenocytes
For other applications, we recommend the unconjugated version of this antibody, 65047-1-Ig

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL647-65047 targets CD103 in FC applications and shows reactivity with Mouse samples.

Tested Applications FC Application Description
Tested Reactivity Mouse
Immunogen C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) 种属同源性预测
Host / Isotype Hamster / IgG
Class Monoclonal
Type Antibody
Full Name integrin alpha E, epithelial-associated
Synonyms A530055J10, alpha E1, alpha M290, aM290, CD103, Integrin alpha E, Itgae
GenBank Accession NumberBC150690
Gene Symbol CD103
Gene ID (NCBI) 16407
RRIDAB_2883652
Conjugate CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission Maxima Wavelengths654 nm / 674 nm
Form Liquid
Purification MethodAffinity purification
UNIPROT IDQ60677
Storage Buffer PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).

实验方案

Product Specific Protocols
FC protocol for CL Plus 647 CD103 antibody CL647-65047Download protocol
Standard Protocols
Click here to view our Standard Protocols