CoraLite® Plus 647 Anti-Mouse CD103 (2E7)
CD103 Monoclonal Antibody for FC
Host / Isotype
Hamster / IgG
Reactivity
Mouse
Applications
FC
Conjugate
CoraLite® Plus 647 Fluorescent Dye
CloneNo.
2E7
验证数据展示
经过测试的应用
Positive FC detected in | mouse splenocytes |
For other applications, we recommend the unconjugated version of this antibody, 65047-1-Ig
推荐稀释比
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL647-65047 targets CD103 in FC applications and shows reactivity with Mouse samples.
Tested Applications | FC Application Description |
Tested Reactivity | Mouse |
Immunogen | C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) 种属同源性预测 |
Host / Isotype | Hamster / IgG |
Class | Monoclonal |
Type | Antibody |
Full Name | integrin alpha E, epithelial-associated |
Synonyms | A530055J10, alpha E1, alpha M290, aM290, CD103, Integrin alpha E, Itgae |
GenBank Accession Number | BC150690 |
Gene Symbol | CD103 |
Gene ID (NCBI) | 16407 |
RRID | AB_2883652 |
Conjugate | CoraLite® Plus 647 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
Form | Liquid |
Purification Method | Affinity purification |
UNIPROT ID | Q60677 |
Storage Buffer | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).
实验方案
Product Specific Protocols | |
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FC protocol for CL Plus 647 CD103 antibody CL647-65047 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |