APC-Cyanine7 Anti-Human CD11a (TS2/4) Mouse IgG2a Recombinant Antibody
CD11a Recombinant Antibody for FC
Host / Isotype
Mouse / IgG2a
Reactivity
Human
Applications
FC
Conjugate
APC-Cyanine7 Fluorescent Dye
CloneNo.
TS2/4
验证数据展示
经过测试的应用
Positive FC detected in | human PBMCs |
推荐稀释比
Application | Dilution |
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This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
AY7-65563 targets CD11a in FC applications and shows reactivity with Human samples.
Tested Applications | FC Application Description |
Tested Reactivity | Human |
Immunogen | HLA-DR CTL line 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Recombinant |
Type | Antibody |
Full Name | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
Synonyms | CD11A, Integrin alpha L, ITGAL, LFA 1, LFA 1A, LFA1A |
Calculated Molecular Weight | 129 kDa |
GenBank Accession Number | BC008777 |
Gene Symbol | CD11a |
Gene ID (NCBI) | 3683 |
ENSEMBL Gene ID | ENSG00000005844 |
Conjugate | APC-Cyanine7 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 650 nm / 778 nm |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P20701 |
Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA. |
Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).
实验方案
Product Specific Protocols | |
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FC protocol for APC-Cyanine7 CD11a antibody AY7-65563 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |