验证数据展示
经过测试的应用
Positive IF-P detected in | human tonsillitis tissue |
推荐稀释比
应用 | 推荐稀释比 |
---|---|
Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
IF | See 3 publications below |
产品信息
CL488-60258 targets CD11c/Integrin Alpha X in IF-P applications and shows reactivity with human samples.
经测试应用 | IF-P Application Description |
文献引用应用 | IF |
经测试反应性 | human |
文献引用反应性 | human |
免疫原 | CD11c/Integrin Alpha X fusion protein Ag11350 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | integrin, alpha X (complement component 3 receptor 4 subunit) |
别名 | CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6 |
计算分子量 | 1169 aa, 129 kDa |
GenBank蛋白编号 | BC038237 |
基因名称 | CD11c |
Gene ID (NCBI) | 3687 |
ENSEMBL Gene ID | ENSG00000140678 |
RRID | AB_2883128 |
偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
最大激发/发射波长 | 493 nm / 522 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P20702 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a 145-150 kDa type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis. And this anitbody is CL488(Ex/Em 488 nm/515 nm) conjugated.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 CD11c/Integrin Alpha X antibody CL488-60258 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Clin Cancer Res 18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition. | ||
Respir Res TFEB regulates dendritic cell antigen presentation to modulate immune balance in asthma | ||
Inflamm Res Long-chain acyl-CoA synthetase 4-mediated mitochondrial fatty acid metabolism and dendritic cell antigen presentation |