CoraLite®594-conjugated CD11c/Integrin Alpha X Monoclonal antibody

CD11c/Integrin Alpha X Monoclonal Antibody for IF-P
Cat No. CL594-60258

产品说明书

CloneNo. 2F1C10

宿主/亚型

Mouse / IgG2a

种属反应性

human and More (1)

应用

IF-P and More (1)

CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive IF-P detected inhuman tonsillitis tissue
Planning an IHC experiment? We recommend our IHCeasy CD11c Ready-To-Use IHC Kit. CD11c primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 60258-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IFSee 2 publications below

产品信息

CL594-60258 targets CD11c/Integrin Alpha X in IF-P applications and shows reactivity with human samples.

经测试应用 IF-P Application Description
文献引用应用IF
经测试反应性 human
文献引用反应性mouse
免疫原 CD11c/Integrin Alpha X fusion protein Ag11350 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 integrin, alpha X (complement component 3 receptor 4 subunit)
别名 CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6
计算分子量 1169 aa, 129 kDa
GenBank蛋白编号BC038237
基因名称 CD11c
Gene ID (NCBI) 3687
ENSEMBL Gene IDENSG00000140678
RRIDAB_2883450
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP20702
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a 145-150 kDa type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis. And this anitbody is CL594(Ex/Em 593 nm/614 nm) conjugated.

实验方案

Product Specific Protocols
IF protocol for CL594 CD11c/Integrin Alpha X antibody CL594-60258Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

JCI Insight

Acquired Immunostimulatory Phenotype of Migratory CD103+ Dendritic Cells Promotes Alloimmunity Following Corneal Transplantation

Authors - Tomas Blanco
mouseIF

Mucosal Immunol

Conventional type I migratory CD103+ dendritic cells are required for corneal allograft survival

Authors - Tomas Blanco
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