CoraLite® Plus 488 Anti-Mouse CD18 (M18/2)

CD18 Monoclonal Antibody for FC
Cat No. CL488-65178
CloneNo. M18/2

Host / Isotype

Rat / IgG2a, kappa

Reactivity

Mouse

Applications

FC

2E6, AI528527, Cd18, integrin beta 2, Itgb2, LAD, LCAMB, Lfa1, MF17

Formulation:  PBS and Azide
PBS and Azide
Size: 

-/ -


经过测试的应用

Positive FC detected inmouse thymocytes
For other applications, we recommend the unconjugated version of this antibody, 65178-1-Ig

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-65178 targets CD18 in FC applications and shows reactivity with Mouse samples.

Tested Applications FC Application Description
Tested Reactivity Mouse
Immunogen Mouse CTL glycoprotein 种属同源性预测
Host / Isotype Rat / IgG2a, kappa
Class Monoclonal
Type Antibody
Full Name integrin beta 2
Synonyms 2E6, AI528527, Cd18, integrin beta 2, Itgb2, LAD, LCAMB, Lfa1, MF17
GenBank Accession NumberBC145644
Gene Symbol CD18
Gene ID (NCBI) 16414
RRIDAB_2934436
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodPurified by protein-A affinity chromatography
UNIPROT IDP11835
Storage Buffer PBS with 0.1% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).

实验方案

Product Specific Protocols
FC protocol for CL Plus 488 CD18 antibody CL488-65178Download protocol
Standard Protocols
Click here to view our Standard Protocols
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