验证数据展示
经过测试的应用
| Positive FC detected in | human monocyte-derived immature dendritic cells |
For other applications, we recommend the unconjugated version of this antibody, 98156-1-PBS
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-98156 targets CD209 in FC applications and shows reactivity with human samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | human |
| Immunogen | Recombinant protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | CD209 molecule |
| Synonyms | DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN |
| Calculated Molecular Weight | 404 aa, 45.7 kDa |
| GenBank Accession Number | BC110615 |
| Gene Symbol | CD209 |
| Gene ID (NCBI) | 30835 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9NNX6 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CL594 CD209 antibody CL594-98156 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |