Anti-Mouse CD30/TNFRSF8 Rabbit Recombinant Antibody
CD30/TNFRSF8 Uni-rAbTM Recombinant Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
mouse
Applications
FC
Conjugate
Unconjugated
CloneNo.
241710B4
验证数据展示
经过测试的应用
| Positive FC detected in | Anti-CD3/CD28 treated mouse splenocytes |
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
98209-1-RR targets CD30/TNFRSF8 in FC applications and shows reactivity with mouse samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | mouse |
| Immunogen | Recombinant protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | tumor necrosis factor receptor superfamily, member 8 |
| Synonyms | Tumor necrosis factor receptor superfamily member 8, Tnfrsf8, Lymphocyte activation antigen CD30, CD30L receptor, CD30 |
| Calculated Molecular Weight | 53kDa |
| GenBank Accession Number | NM_009401.2 |
| Gene Symbol | Tnfrsf8 |
| Gene ID (NCBI) | 21941 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q60846 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
背景介绍
CD30, also known as TNFRSF8 or Ki-1, is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is composed of an extracellular domain with six cysteine-rich repeats, a transmembrane segment, and an intracellular domain (PMID: 1310894). CD30 is expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (PMID: 9826579; 28885612). The CD30 ligand (CD30L or CD153) is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily (PMID: 8701986). Signal transduction of CD30/CD30L utilizes signal transducers, TNFR-associated factors (TRAF1, 2, 3 and 5) (PMID: 9826579).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CD30/TNFRSF8 antibody 98209-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |