Anti-Rat CD44 Rabbit Recombinant Antibody, PBS Only
CD44 Uni-rAbTM Recombinant Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
rat
Applications
FC
Conjugate
Unconjugated
CloneNo.
241648F8
验证数据展示
产品信息
98208-1-PBS targets CD44 in FC applications and shows reactivity with rat samples.
Tested Applications | FC Application Description |
Tested Reactivity | rat |
Immunogen | Recombinant protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | Cd44 molecule |
Synonyms | Hermes antigen, GP90 lymphocyte homing/adhesion receptor, Extracellular matrix receptor III, ECMR-III, CD44 antigen |
Calculated Molecular Weight | 40 kDa |
GenBank Accession Number | XM_006234631.3 |
Gene Symbol | Cd44 |
Gene ID (NCBI) | 25406 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | O70509 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.