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Host
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Species Reactivity
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验证数据展示

  • WB analysis using 84507-4-RR (same clone as 84507-4-PBS)

    WB analysis using 84507-4-RR (same clone as 84507-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84507-4-RR (CD63 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84507-4-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 84507-4-RR (same clone as 84507-4-PBS)

    IHC staining of human tonsillitis using 84507-4-RR (same clone as 84507-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84507-4-RR (CD63 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84507-4-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD63 antibody included
  • IF Staining of A431 using 84507-4-RR (same clone as 84507-4-PBS)

    IF Staining of A431 using 84507-4-RR (same clone as 84507-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using CD63 antibody (84507-4-RR, Clone: 241964H1 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84507-4-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 84507-4-RR (same clone as 84507-4-PBS)

    IHC staining of human tonsillitis using 84507-4-RR (same clone as 84507-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84507-4-RR (CD63 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84507-4-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD63 antibody included

CD63 Recombinant antibody, PBS Only

CD63 Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 84507-4-PBS

产品说明书

CloneNo. 241964H1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

Lysosome integral membrane protein 1, Lysosomal-associated membrane protein 3, Limp1, CD63 antigen, CD 63

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CD63 Ready-To-Use IHC Kit. CD63 primary antibody included.

产品信息

84507-4-PBS targets CD63 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 FusionProtein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD63 molecule
别名 Lysosome integral membrane protein 1, Lysosomal-associated membrane protein 3, Limp1, CD63 antigen, CD 63
计算分子量 26 kDa
观测分子量30-60 kDa
GenBank蛋白编号BC002349
基因名称 CD63
Gene ID (NCBI) 967
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP08962
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD63 is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediates signal transduction events that regulate cell development, activation, growth, and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein translocated to the plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it is a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome.