Anti-Human CD68 (Y1/82A)

CD68 Monoclonal Antibody for IF/ICC, FC (Intra)
Cat No. 65187-1-Ig

产品说明书

CloneNo. Y1/82A

宿主/亚型

Mouse / IgG2b, kappa

种属反应性

human

应用

IF/ICC, FC (Intra) and More (3)

Y1/82A, SCARD1, Macrosialin, GP110, CD68 molecule

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inTHP-1 cells
Positive FC (Intra) detected inhuman PBMCs
Positive FC detected inhuman PBMCs
Planning an IHC experiment? We recommend our IHCeasy CD68 Ready-To-Use IHC Kit. CD68 primary antibody included.

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65187-1-Ig targets CD68 in WB, IHC, IF/ICC, FC (Intra) applications and shows reactivity with human samples.

经测试应用 IF/ICC, FC (Intra) Application Description
文献引用应用WB, IHC, IF
经测试反应性 human
文献引用反应性human
免疫原 Lysosomal contents of lung macrophages 种属同源性预测
宿主/亚型 Mouse / IgG2b, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 CD68 molecule
别名 Y1/82A, SCARD1, Macrosialin, GP110, CD68 molecule
计算分子量 37 kDa
GenBank蛋白编号BC015557
基因名称 CD68
Gene ID (NCBI) 968
RRIDAB_2918458
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP34810
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Stable for one year after shipment.

背景介绍

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.

实验方案

Product Specific Protocols
IF protocol for CD68 antibody 65187-1-IgDownload protocol
FC protocol for CD68 antibody 65187-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
IF

Int Immunopharmacol

Diosgenin alters LPS-induced macrophage polarization by activating PPARγ/NF-κB signaling pathway

Authors - Xingchen Xiang
IF

Phytomedicine

Koumine regulates macrophage M1/M2 polarization via TSPO, alleviating sepsis-associated liver injury in mice

Authors - Gui-Lin Jin

Int Immunopharmacol

Macrophages regulates the transition of pericyte to peritoneal fibrosis through the GSDMD/IL-1β axis

Authors - Qiuyuan Shao
humanIF

Hepatology

Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis

Authors - Xianzhi Liu
IF

Exp Neurol

Microglia trigger the structural plasticity of GABAergic neurons in the hippocampal CA1 region of a lipopolysaccharide-induced neuroinflammation model

Authors - Juan Chen
WB,IHC

Int Immunopharmacol

Inhibition of aquaporin-9 ameliorates severe acute pancreatitis and associated lung injury by NLRP3 and Nrf2/HO-1 pathways

Authors - Jiawei Chen
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