验证数据展示
产品信息
66928-1-PBS targets CFTR in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.
经测试应用 | WB, IHC, ELISA Application Description |
经测试反应性 | human, mouse, rat, rabbit |
免疫原 | CFTR fusion protein Ag27810 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
别名 | Channel conductance-controlling ATPase, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette sub-family C member 7, ABCC7 |
计算分子量 | 168 kDa |
观测分子量 | 150 kDa |
GenBank蛋白编号 | NM_000492 |
基因名称 | CFTR |
Gene ID (NCBI) | 1080 |
RRID | AB_2882254 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P13569 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CFTR is a member of the ATP-binding cassette (ABC) family of membrane transport proteins, functioning as a chloride channel responsible for ion flow across epithelial surfaces of lung, sinuses, pancreas, intestine, and liver. Mutations of CFTR cause cystic fibrosis (CF), a disorder affecting the respiratory, digestive, reproductive systems and sweat glands.