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  • Featured Product
  • KD/KO Validated

CFTR Monoclonal antibody, PBS Only

CFTR Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, rabbit

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

2F4A8

Cat no : 66928-1-PBS

Print datasheet

Synonyms

Channel conductance-controlling ATPase, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette sub-family C member 7, ABCC7

验证数据展示

  • WB analysis using 66928-1-Ig (same clone as 66928-1-PBS)

    WB analysis using 66928-1-Ig (same clone as 66928-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66928-1-Ig (CFTR antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66928-1-PBS in a different storage buffer formulation.

  • WB analysis using 66928-1-Ig (same clone as 66928-1-PBS)

    WB analysis using 66928-1-Ig (same clone as 66928-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66928-1-Ig (CFTR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66928-1-PBS in a different storage buffer formulation.

  • WB analysis using 66928-1-Ig (same clone as 66928-1-PBS)

    WB analysis using 66928-1-Ig (same clone as 66928-1-PBS)

    WB result of CFTR antibody (66928-1-Ig; 1:4000; room temperature for 1.5 hours) with wild-type and CFTR knockout HEK-293T cells. This data was developed using the same antibody clone with 66928-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung using 66928-1-Ig (same clone as 66928-1-PBS)

    IHC staining of human lung using 66928-1-Ig (same clone as 66928-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung tissue slide using 66928-1-Ig (CFTR antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66928-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CFTR antibody included
  • IHC staining of human lung using 66928-1-Ig (same clone as 66928-1-PBS)

    IHC staining of human lung using 66928-1-Ig (same clone as 66928-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung tissue slide using 66928-1-Ig (CFTR antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66928-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CFTR antibody included
Planning an IHC experiment? We recommend our IHCeasy CFTR Ready-To-Use IHC Kit. CFTR primary antibody included.

产品信息

66928-1-PBS targets CFTR in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity human, mouse, rat, rabbit
Immunogen CFTR fusion protein Ag27810 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Synonyms Channel conductance-controlling ATPase, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette sub-family C member 7, ABCC7
Calculated Molecular Weight 168 kDa
Observed Molecular Weight 150 kDa
GenBank Accession NumberNM_000492
Gene Symbol CFTR
Gene ID (NCBI) 1080
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP13569
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CFTR is a member of the ATP-binding cassette (ABC) family of membrane transport proteins, functioning as a chloride channel responsible for ion flow across epithelial surfaces of lung, sinuses, pancreas, intestine, and liver. Mutations of CFTR cause cystic fibrosis (CF), a disorder affecting the respiratory, digestive, reproductive systems and sweat glands.