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CLEC10A/CD301 Recombinant antibody

CLEC10A/CD301 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241857C11

Cat no : 98245-1-RR

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Synonyms

CLEC10A, C-type lectin domain family 10 member A, CLECSF14, CLECSF13, CD301

验证数据展示

  • FC experiment of Human immature monocyte-derived dendritic cells using 98245-1-RR

    FC experiment of Human immature monocyte-derived dendritic cells using 98245-1-RR

    1x10^6 Human immature monocyte-derived dendritic cells were surface stained with 0.25 ug Anti-Human CLEC10A/CD301 Rabbit Recombinant Antibody (98245-1-RR, Clone: 241857C11) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • Affinity and Kinetic Characterization of 98245-1-RR

    Affinity and Kinetic Characterization of 98245-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98245-1-RR against Human CLEC10A/CD301 were performed. The affinity constant is below 1 pM.

经过测试的应用

Positive FC detected inHuman immature monocyte-derived dendritic cells

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98245-1-RR targets CLEC10A/CD301 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name C-type lectin domain family 10, member A
Synonyms CLEC10A, C-type lectin domain family 10 member A, CLECSF14, CLECSF13, CD301
Calculated Molecular Weight 316 aa, 35 kDa
GenBank Accession NumberBC039011
Gene Symbol CLEC10A
Gene ID (NCBI) 10462
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ8IUN9
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

背景介绍

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).

实验方案

Product Specific Protocols
FC protocol for CLEC10A/CD301 antibody 98245-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols