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验证数据展示

  • FC experiment of Human immature monocyte-derived dendritic cells using 98245-1-RR (same clone as 98245-1-PBS)

    FC experiment of Human immature monocyte-derived dendritic cells using 98245-1-RR (same clone as 98245-1-PBS)

    1x10^6 Human immature monocyte-derived dendritic cells were surface stained with 0.25 ug Anti-Human CLEC10A/CD301 Rabbit Recombinant Antibody (98245-1-RR, Clone: 241857C11) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98245-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98245-1-RR

    Affinity and Kinetic Characterization of 98245-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98245-1-RR against Human CLEC10A/CD301 were performed. The affinity constant is below 1 pM.

Anti-Human CLEC10A/CD301 Rabbit Recombinant Antibody, PBS Only

CLEC10A/CD301 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98245-1-PBS

产品说明书

CloneNo. 241857C11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CLEC10A, C-type lectin domain family 10 member A, CLECSF14, CLECSF13, CD301

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98245-1-PBS targets CLEC10A/CD301 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 C-type lectin domain family 10, member A
别名 CLEC10A, C-type lectin domain family 10 member A, CLECSF14, CLECSF13, CD301
计算分子量 316 aa, 35 kDa
GenBank蛋白编号BC039011
基因名称 CLEC10A
Gene ID (NCBI) 10462
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ8IUN9
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).