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CLEC10A/CD301 Recombinant antibody, PBS Only

CLEC10A/CD301 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241857C11

Cat no : 98245-1-PBS

Print datasheet

Synonyms

CLEC10A, C-type lectin domain family 10 member A, CLECSF14, CLECSF13, CD301

验证数据展示

  • FC experiment of Human immature monocyte-derived dendritic cells using 98245-1-RR (same clone as 98245-1-PBS)

    FC experiment of Human immature monocyte-derived dendritic cells using 98245-1-RR (same clone as 98245-1-PBS)

    1x10^6 Human immature monocyte-derived dendritic cells were surface stained with 0.25 ug Anti-Human CLEC10A/CD301 Rabbit Recombinant Antibody (98245-1-RR, Clone: 241857C11) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98245-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98245-1-RR

    Affinity and Kinetic Characterization of 98245-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98245-1-RR against Human CLEC10A/CD301 were performed. The affinity constant is below 1 pM.

产品信息

98245-1-PBS targets CLEC10A/CD301 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name C-type lectin domain family 10, member A
Synonyms CLEC10A, C-type lectin domain family 10 member A, CLECSF14, CLECSF13, CD301
Calculated Molecular Weight 316 aa, 35 kDa
GenBank Accession NumberBC039011
Gene Symbol CLEC10A
Gene ID (NCBI) 10462
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ8IUN9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).