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Conjugate
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验证数据展示

  • WB analysis using 83312-1-RR (same clone as 83312-1-PBS)

    WB analysis using 83312-1-RR (same clone as 83312-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83312-1-RR (COPS8 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83312-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 83312-1-RR (same clone as 83312-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 83312-1-RR (same clone as 83312-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 83312-1-RR (COPS8 antibody) at dilution of 1:250 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83312-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 83312-1-RR (same clone as 83312-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 83312-1-RR (same clone as 83312-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 83312-1-RR (COPS8 antibody) at dilution of 1:250 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83312-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 83312-1-RR (same clone as 83312-1-PBS)

    IF Staining of SH-SY5Y using 83312-1-RR (same clone as 83312-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed SH-SY5Y cells using COPS8 antibody (83312-1-RR, Clone: 240195B1 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 83312-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00336-2

    Cytometric bead array standard curve of MP00336-2

    Cytometric bead array standard curve of MP00336-2, COPS8 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83312-2-PBS. Detection antibody: 83312-1-PBS. Standard: Ag0143. Range: 0.625-40 ng/mL.

  • Affinity and Kinetic Characterization of 83312-1-RR

    Affinity and Kinetic Characterization of 83312-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83312-1-RR against Human COPS8 were performed. The affinity constant is 1.67 nM.

COPS8 Recombinant antibody, PBS Only (Detector)

COPS8 Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA
Cat No. 83312-1-PBS

产品说明书

CloneNo. 240195B1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA

别名

COP9, 240195B1, JAB1-containing signalosome subunit 8, hCOP9, CSN8

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83312-1-PBS targets COPS8 as part of a matched antibody pair:

MP00336-2: 83312-2-PBS capture and 83312-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 COPS8 fusion protein Ag0143 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
别名 COP9, 240195B1, JAB1-containing signalosome subunit 8, hCOP9, CSN8
计算分子量 23 kDa
观测分子量23 kDa
GenBank蛋白编号BC003090
基因名称 COPS8
Gene ID (NCBI) 10920
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99627
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

COPS8 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.