• Featured Product
  • KD/KO验证

CoraLite® Plus 488-conjugated CSDE1 Polyclonal antibody

CSDE1 Polyclonal Antibody for IF/ICC
Cat No. CL488-13319

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IF/ICC

CSDE1, D1S155E, DKFZp779B0247, DKFZp779J1455, FLJ26882, KIAA0885, N ras upstream gene protein, NRU, Protein UNR, RP5 1000E10.3, UNR

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy CSDE1 Ready-To-Use IHC Kit. CSDE1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 13319-1-AP

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-13319 targets CSDE1 in IF/ICC applications and shows reactivity with human, mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse
免疫原 CSDE1 fusion protein Ag4173 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cold shock domain containing E1, RNA-binding
别名 CSDE1, D1S155E, DKFZp779B0247, DKFZp779J1455, FLJ26882, KIAA0885, N ras upstream gene protein, NRU, Protein UNR, RP5 1000E10.3, UNR
计算分子量 798 aa, 89 kDa
观测分子量 89 kDa
GenBank蛋白编号BC032446
基因名称 CSDE1
Gene ID (NCBI) 7812
RRIDAB_3672561
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75534
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CSDE1 (Cold shock domain-containing protein E1), also known as UNR (upstream of N-ras), is an RNA-binding protein involved in the regulation of messenger RNA stability and internal initiation of translation. It is required for internal initiation of translation of human rhinovirus RNA. UNR may be involved in translationally coupled mRNA turnover. Reduced expression of UNR impairs proliferation and differentiation of erythroid blasts. Recent study found that UNR acts as a positive or negative regulator of cell death, depending on the cell type, suggesting manipulation of UNR level may constitute a specific approach to sensitize cancer cells to anticancer treatments.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 CSDE1 antibody CL488-13319Download protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...