验证数据展示
经过测试的应用
Positive IF/ICC detected in | A549 cells |
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-12286 targets CYP4F11 in IF/ICC applications and shows reactivity with human samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | human |
Immunogen | CYP4F11 fusion protein Ag2906 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | cytochrome P450, family 4, subfamily F, polypeptide 11 |
Synonyms | CYP4F11, CYPIVF11, Cytochrome P450 4F11 |
Calculated Molecular Weight | 524 aa, 60 kDa |
Observed Molecular Weight | 57 kDa |
GenBank Accession Number | BC016853 |
Gene Symbol | CYP4F11 |
Gene ID (NCBI) | 57834 |
RRID | AB_3672532 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9HBI6 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CYP4F11, also named as CYPIVF11, belongs to the cytochrome P450 family. It is the lone CYP4F/A enzyme that effectively oxidized 3-hydroxypalmitate. It is the predominant catalyst of this fatty acid oxidation reaction in human liver. CYP4F11 is one of the primary human epidermal keratinocytes. It is positively regulated by multiple signaling pathways in HaCaT keratinocytes, including RXR and JNK signaling pathways. (PMID:19812349)
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 CYP4F11 antibody CL488-12286 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |