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Host
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Conjugate
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Conjugate
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验证数据展示

  • WB analysis of PC-3 using 12028-1-AP (same clone as 12028-1-PBS)

    WB analysis of PC-3 using 12028-1-AP (same clone as 12028-1-PBS)

    PC-3 cells were subjected to SDS PAGE followed by western blot with 12028-1-AP (Cadherin-11 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12028-1-PBS in a different storage buffer formulation.

Cadherin-11 Polyclonal antibody, PBS Only

Cadherin-11 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 12028-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

CDH11, CAD11, Cadherin 11, CDHOB, OB

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

12028-1-PBS targets Cadherin-11 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Cadherin-11 fusion protein Ag2659 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cadherin 11, type 2, OB-cadherin (osteoblast)
别名 CDH11, CAD11, Cadherin 11, CDHOB, OB
计算分子量 796 aa, 88 kDa
观测分子量120 kDa
GenBank蛋白编号BC013609
基因名称 CDH11
Gene ID (NCBI) 1009
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP55287
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Cadherin-11 (CDH11), also known osteoblast cadherin (OB-cadherin) or OSF-4, was identified initially in a mouse osteoblastic cell line and human osteosarcoma (PMID: 8163513). Cadherin-11 is a single pass transmembrane protein consisting of an extracellular domain which contains five repeat sequences (EC1-EC5), a transmembrane segment and a cytoplasmic domain which links catenins to the actin and microtubule cytoskeleton (PMID: 8163513; 33442417). It has been shown that cadherin-11 plays important roles in the occurrence and development of a lot of diseases, arthritis, cancer, aortic calcification disease, dermatosis (PMID: 33442417).