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验证数据展示

  • FC experiment of human PBMCs using 98261-1-RR (same clone as 98261-1-PBS)

    FC experiment of human PBMCs using 98261-1-RR (same clone as 98261-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DPP4/CD26 Rabbit Recombinant Antibody (98261-1-RR, Clone: 242045C1) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (APC-65569, Clone: OKT3). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98261-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98261-1-RR (same clone as 98261-1-PBS)

    FC experiment of human PBMCs using 98261-1-RR (same clone as 98261-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DPP4/CD26 Rabbit Recombinant Antibody (98261-1-RR, Clone: 242045C1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98261-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98261-1-RR

    Affinity and Kinetic Characterization of 98261-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98261-1-RR against Human DPP4/CD26 were performed. The affinity constant is 2.22 nM.

Anti-Human DPP4/CD26 Rabbit Recombinant Antibody, PBS Only

DPP4/CD26 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98261-1-PBS

产品说明书

CloneNo. 242045C1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CD26, ADCP-2, ADCP2, ADCP 2, ADABP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98261-1-PBS targets DPP4/CD26 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 dipeptidyl-peptidase 4
别名 CD26, ADCP-2, ADCP2, ADCP 2, ADABP
计算分子量 88 kDa
GenBank蛋白编号BC013329
基因名称 DPP4
Gene ID (NCBI) 1803
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP27487
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD26, also known as DPP4 (dipeptidyl peptidase-4), is a 110 kDa type II cell-surface glycoprotein widely expressed on T cells, activated B cells, activated NK cells and myeloid cells as well as on epithelial cells, fibroblasts, mesothelium, and endothelial cells of a variety of tissues (PMID:33777580; 26919392). It has ecto-enzyme activity in its extracellular domain and cleaves amino-terminal dipeptides with either L-proline or L-alanine at the penultimate position (PMID: 9553764). CD26 plays roles in diverse biological processes such as immunoregulation, glucose homeostasis, and tumorigenesis (PMID: 33777580).