验证数据展示
产品信息
67672-1-PBS targets DVL1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human, rat, mouse |
免疫原 | DVL1 fusion protein Ag26083 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | dishevelled, dsh homolog 1 (Drosophila) |
别名 | Dishevelled 1, DSH homolog 1, DVL, DVL1 |
计算分子量 | 75 kDa |
观测分子量 | 70-75 kDa |
GenBank蛋白编号 | BC050454 |
基因名称 | DVL1 |
Gene ID (NCBI) | 1855 |
RRID | AB_2882868 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | O14640 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DVL1 is one of three DVL homologous proteins (DVL1-3) widely expressed in embryonic development and in the adult central nervous system. Dishevelled proteins are a necessary component of the Wnt and planar cell polarity developmental signaling pathways. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway. There are two isoforms of DVL1: 75 kDa and 73 kDa.