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DVL1 Monoclonal antibody, PBS Only

DVL1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A2A5

Cat no : 67672-1-PBS

Print datasheet

Synonyms

Dishevelled 1, DSH homolog 1, DVL, DVL1

验证数据展示

  • WB analysis using 67672-1-Ig (same clone as 67672-1-PBS)

    WB analysis using 67672-1-Ig (same clone as 67672-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67672-1-Ig (DVL1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67672-1-PBS in a different storage buffer formulation.

  • IHC staining of rat colon using 67672-1-Ig (same clone as 67672-1-PBS)

    IHC staining of rat colon using 67672-1-Ig (same clone as 67672-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat colon tissue slide using 67672-1-Ig (DVL1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67672-1-PBS in a different storage buffer formulation.

  • IHC staining of rat colon using 67672-1-Ig (same clone as 67672-1-PBS)

    IHC staining of rat colon using 67672-1-Ig (same clone as 67672-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat colon tissue slide using 67672-1-Ig (DVL1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67672-1-PBS in a different storage buffer formulation.

产品信息

67672-1-PBS targets DVL1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, rat, mouse
Immunogen DVL1 fusion protein Ag26083 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name dishevelled, dsh homolog 1 (Drosophila)
Synonyms Dishevelled 1, DSH homolog 1, DVL, DVL1
Calculated Molecular Weight 75 kDa
Observed Molecular Weight70-75 kDa
GenBank Accession NumberBC050454
Gene Symbol DVL1
Gene ID (NCBI) 1855
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO14640
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DVL1 is one of three DVL homologous proteins (DVL1-3) widely expressed in embryonic development and in the adult central nervous system. Dishevelled proteins are a necessary component of the Wnt and planar cell polarity developmental signaling pathways. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway. There are two isoforms of DVL1: 75 kDa and 73 kDa.