验证数据展示
产品信息
67672-1-PBS targets DVL1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | Human, rat, mouse |
Immunogen | DVL1 fusion protein Ag26083 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | dishevelled, dsh homolog 1 (Drosophila) |
Synonyms | Dishevelled 1, DSH homolog 1, DVL, DVL1 |
Calculated Molecular Weight | 75 kDa |
Observed Molecular Weight | 70-75 kDa |
GenBank Accession Number | BC050454 |
Gene Symbol | DVL1 |
Gene ID (NCBI) | 1855 |
RRID | AB_2882868 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | O14640 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DVL1 is one of three DVL homologous proteins (DVL1-3) widely expressed in embryonic development and in the adult central nervous system. Dishevelled proteins are a necessary component of the Wnt and planar cell polarity developmental signaling pathways. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway. There are two isoforms of DVL1: 75 kDa and 73 kDa.