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Drebrin Monoclonal antibody, PBS Only

Drebrin Monoclonal Antibody for WB,IHC,IF,ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat, pig

Applications

WB,IHC,IF,ELISA

Conjugate

Unconjugated

CloneNo.

1A12H1

Cat No : 67589-1-PBS

Print datasheet

Synonyms

D0S117E, DBN1, DKFZp434D064, Drebrin, drebrin 1

验证数据展示

  • WB analysis using 67589-1-Ig (same clone as 67589-1-PBS)

    WB analysis using 67589-1-Ig (same clone as 67589-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67589-1-Ig (Drebrin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67589-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 67589-1-Ig (same clone as 67589-1-PBS)

    IHC staining of mouse brain using 67589-1-Ig (same clone as 67589-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67589-1-Ig (Drebrin antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67589-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with DBN1/Drebrin antibody included
  • IF Staining of mouse brain using 67589-1-Ig (same clone as 67589-1-PBS)

    IF Staining of mouse brain using 67589-1-Ig (same clone as 67589-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using Drebrin antibody (67589-1-Ig, Clone: 1A12H1 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). DAPI (blue). This data was developed using the same antibody clone with 67589-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy DBN1/Drebrin Ready-To-Use IHC Kit. DBN1/Drebrin primary antibody included.

产品信息

67589-1-PBS targets Drebrin in WB, IF, IHC, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Applications WB,IHC,IF,ELISA Application Description
Tested Reactivity Human, mouse, rat, pig
Immunogen Drebrin fusion protein Ag22635 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name drebrin 1
Synonyms D0S117E, DBN1, DKFZp434D064, Drebrin, drebrin 1
Observed Molecular Weight 110-120 kDa
GenBank Accession NumberBC007567
Gene Symbol DBN1
Gene ID (NCBI) 1627
ENSEMBL Gene IDENSG00000113758
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ16643
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

背景介绍

Drebrin (DBN1) is an actin binding and stabilizing protein with roles in endocytosis, formation of dendrite spines in neurons and coordinating cell-cell synapses in immune cells. Preferentially expressed in the brain, it is highly localized in dendritic spines and regulates spine shapes. It has two isoforms that are splice variants, with drebrin A being expressed in neural cells, and drebrin E is present in several other cell types. Recently it has been reported that circulating DBN1 levels correlated with retinal nerve fiber layer defect and may reflect the severity of retinal ganglion cells injury in glaucoma patients.