验证数据展示
经过测试的应用
Positive IF/ICC detected in | HepG2 cells |
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL555-67986 targets FAH in IF/ICC applications and shows reactivity with Human, pig, rat, mouse samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | Human, pig, rat, mouse |
Immunogen | FAH fusion protein Ag6704 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
Synonyms | Beta diketonase, FAA, FAH, Fumarylacetoacetase, Fumarylacetoacetate hydrolase |
Calculated Molecular Weight | 46 kDa |
Observed Molecular Weight | 40-45 kDa |
GenBank Accession Number | BC002527 |
Gene Symbol | FAH |
Gene ID (NCBI) | 2184 |
RRID | AB_2934687 |
Conjugate | CoraLite®555 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 557 nm / 570nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P16930 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
FAH is also named as FAA(fumarylacetoacetase), the last enzyme in tyrosine degradation, functionally important in the liver and kidney(PMID:8473520). FAH is a metabolic enzyme catalyzing the last step of tyrosine and phenylalanine catabolism: the hydrolysis of fumarylacetoacetate into acetoacetate and fumarate. In humans, deficiency of this activity is associated with the metabolic disease hereditary tyrosinaemia type I, which is also known as hepatorenal tyrosinaemia(PMID:17768357).
实验方案
Product Specific Protocols | |
---|---|
IF protocol for CL555 FAH antibody CL555-67986 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |