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验证数据展示

  • IF Staining of mouse skeletal muscle using CL594-67172

    IF Staining of mouse skeletal muscle using CL594-67172

    Immunofluorescent analysis of (4% PFA) fixed mouse skeletal muscle tissue using CoraLite®594 FBXO32 antibody (CL594-67172, Clone: 3C2G3 ) at dilution of 1:200.

CoraLite®594-conjugated FBXO32 Monoclonal antibody

FBXO32 Monoclonal Antibody for IF-P
Cat No. CL594-67172

产品说明书

CloneNo. 3C2G3

宿主/亚型

Mouse / IgG2b

种属反应性

Human, mouse

应用

IF-P

别名

Atrogin 1, F box only protein 32, F box protein 32, Fbx32, FBXO32, FLJ32424, MAFbx, Muscle atrophy F box protein

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inmouse skeletal muscle tissue
Planning an IHC experiment? We recommend our IHCeasy FBXO32 Ready-To-Use IHC Kit. FBXO32 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67172-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-67172 targets FBXO32 in IF-P applications and shows reactivity with Human, mouse samples.

经测试应用 IF-P Application Description
经测试反应性 Human, mouse
免疫原 FBXO32 fusion protein Ag25247 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 F-box protein 32
别名 Atrogin 1, F box only protein 32, F box protein 32, Fbx32, FBXO32, FLJ32424, MAFbx, Muscle atrophy F box protein
计算分子量 355 aa, 42 kDa
观测分子量 42 kDa
GenBank蛋白编号BC024030
基因名称 FBXO32
Gene ID (NCBI) 114907
RRIDAB_3084755
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ969P5
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FBXO32 (F box only protein 32), also known as Atrogin 1 or MAFbx, is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif F-box. This protein is an E3 ubiquitin ligase that is markedly up-regulated in muscle atrophy. FBXO32 is thus a potential drug target for the treatment of muscle atrophy. Some data support that FBXO32 may play an important role in tumorigenesis. Recent study reveal that FBXO32 targets the oncogenic protein c-Myc for ubiquitination and degradation through the proteasome pathway.

实验方案

Product Specific Protocols
IF protocol for CL594 FBXO32 antibody CL594-67172Download protocol
Standard Protocols
Click here to view our Standard Protocols