CoraLite® Plus 488-conjugated FIP1L1 Recombinant antibody

FIP1L1 Recombinant Antibody for IF/ICC
Cat No. CL488-83863-3

Print datasheet

CloneNo. 240658A8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC

RHE, Pre-mRNA 3'-end-processing factor FIP1, FIP1-like 1 protein, FIP1, 240658A8

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  CoraLite® Plus 488
Size: 

-/ -


经过测试的应用

Positive IF/ICC detected inMCF-7 cells
Planning an IHC experiment? We recommend our IHCeasy FIP1L1 Ready-To-Use IHC Kit. FIP1L1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 83863-3-PBS

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-83863-3 targets FIP1L1 in IF/ICC applications and shows reactivity with human samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human
Immunogen FIP1L1 fusion protein Ag2921 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name FIP1 like 1 (S. cerevisiae)
Synonyms RHE, Pre-mRNA 3'-end-processing factor FIP1, FIP1-like 1 protein, FIP1, 240658A8
Calculated Molecular Weight 594 aa, 66 kDa
GenBank Accession NumberBC017724
Gene Symbol FIP1L1
Gene ID (NCBI) 81608
RRIDAB_3673317
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ6UN15
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FIP1L1, also known as FIP1, encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that links the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion causes some forms of idiopathic hypereosinophilic syndrome (HES)( PMID: 12660384).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 FIP1L1 antibody CL488-83863-3Download protocol
Standard Protocols
Click here to view our Standard Protocols
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