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  • Featured Product
  • KD/KO Validated

FKBP8 Monoclonal antibody, PBS Only

FKBP8 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C1G12

Cat no : 66690-1-PBS

Print datasheet

Synonyms

FKBP-38, FKBP38, FKBP 8, FKBP 38, FK506-binding protein 8

验证数据展示

  • IHC staining of human hypothalamus using 66690-1-Ig (same clone as 66690-1-PBS)

    IHC staining of human hypothalamus using 66690-1-Ig (same clone as 66690-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human hypothalamus tissue slide using 66690-1-Ig (FKBP8 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66690-1-PBS in a different storage buffer formulation.

  • WB analysis of Jurkat using 66690-1-Ig (same clone as 66690-1-PBS)

    WB analysis of Jurkat using 66690-1-Ig (same clone as 66690-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66690-1-Ig (FKBP8 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66690-1-PBS in a different storage buffer formulation.

  • WB analysis using 66690-1-Ig (same clone as 66690-1-PBS)

    WB analysis using 66690-1-Ig (same clone as 66690-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66690-1-Ig (FKBP8 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66690-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 66690-1-Ig (same clone as 66690-1-PBS)

    IF Staining of A431 using 66690-1-Ig (same clone as 66690-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using FKBP8 antibody (66690-1-Ig, Clone: 1C1G12 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 66690-1-PBS in a different storage buffer formulation.

产品信息

66690-1-PBS targets FKBP8 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen FKBP8 fusion protein Ag1649 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name FK506 binding protein 8, 38kDa
Synonyms FKBP-38, FKBP38, FKBP 8, FKBP 38, FK506-binding protein 8
Calculated Molecular Weight 45 kDa
Observed Molecular Weight 53 kDa
GenBank Accession NumberBC009966
Gene Symbol FKBP8
Gene ID (NCBI) 23770
RRIDAB_2882044
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ14318
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FK506 binding protein 8 (FKBP8), is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP8 does not seem to have PPIase/rotamase activity, which is different from other members of this family. The active form of FKBP8 may play a role in the regulation of apoptosis. FKBP8 has 3 isoforms produced by alternative splicing.