验证数据展示
产品信息
68551-1-PBS targets FMNL2 in WB, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | FMNL2 fusion protein Ag34164 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | formin-like 2 |
别名 | FHOD2, FLJ37546, FMNL2, formin like 2, Formin like protein 2, KIAA1902 |
观测分子量 | 140-150 kDa |
GenBank蛋白编号 | BC167159 |
基因名称 | FMNL2 |
Gene ID (NCBI) | 114793 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q96PY5 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Formin-like 2 (FMNL2), also known as FRL3 or FHOD2, a member of the diaphanous-related formins, contains a GTPase-binding domain and autoregulatory domains, and is proposed to function as a downstream effector of Rho family guanosine triphosphatases (GTPases) (PMID:15950879). FMNL2 mRNA is expressed in many normal tissues and dysregulated in several cancers such as colorectal cancer, melanoma and involved in invasive behaviours and progression of cancer cells.