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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • IHC staining of mouse cerebellum using 21766-1-AP (same clone as 21766-1-PBS)

    IHC staining of mouse cerebellum using 21766-1-AP (same clone as 21766-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 21766-1-AP (GABRA6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21766-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 21766-1-AP (same clone as 21766-1-PBS)

    IHC staining of mouse cerebellum using 21766-1-AP (same clone as 21766-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 21766-1-AP (GABRA6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21766-1-PBS in a different storage buffer formulation.

GABRA6 Polyclonal antibody, PBS Only

GABRA6 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 21766-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

21766-1-PBS targets GABRA6 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 GABRA6 fusion protein Ag16375 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gamma-aminobutyric acid (GABA) A receptor, alpha 6
别名
计算分子量 453 aa, 51 kDa
GenBank蛋白编号BC096241
基因名称 GABRA6
Gene ID (NCBI) 2559
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ16445
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABAA receptors, which are ligand-gated chloride channels. GABAA receptors are formed by pentameric assembly of 19 different subunit subtypes (α1-α6, β1-β3, γ1-γ3, δ, ɛ, π, θ and ρ1-ρ3) (PMID: 21930603). The mutation R46W of GABRA6 is associated with the pathogenesis of childhood absence epilepsy (CAE) (PMID: 21930603).