验证数据展示
产品信息
68051-1-PBS targets GAS2L1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse |
免疫原 | GAS2L1 fusion protein Ag31232 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | growth arrest-specific 2 like 1 |
别名 | GAR22, GAS2 like protein 1, GAS2L1, growth arrest 2 like 1 |
计算分子量 | 73 kDa |
观测分子量 | 73 kDa |
GenBank蛋白编号 | BC011047 |
基因名称 | GAS2L1 |
Gene ID (NCBI) | 10634 |
RRID | AB_2918793 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q99501 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GAS2L1(growth arrest‐specific 2‐like 1) is a component of the cytoskeleton that mediates the interaction between microtubules and microfilament (PMID: 34555082). GAS2L1 contains an N‐terminal actin‐binding calponin homology (CH) domain, a MT lattice‐binding Gas2‐related (GAR) domain and a C‐terminal SxIP motif, which mediates the interaction with MT plus ends via EB proteins. GAS2L1 regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (PubMed:24706950).