CoraLite® Plus 488-conjugated GDNF Recombinant antibody

GDNF Uni-rAbTM Recombinant Antibody for IF/ICC
Cat No. CL488-83087

产品说明书

CloneNo. 230358A10

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IF/ICC

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inSH-SY5Y cells
For other applications, we recommend the unconjugated version of this antibody, 83087-1-PBS

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-83087 targets GDNF in IF/ICC applications and shows reactivity with human, mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse
免疫原 GDNF fusion protein Ag24068 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 glial cell derived neurotrophic factor
别名
计算分子量 211 aa, 24 kDa
观测分子量 32-40 kDa
GenBank蛋白编号BC069369
基因名称 GDNF
Gene ID (NCBI) 2668
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP39905
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Glial-derived neurotrophic factor (GDNF) is a member of the transforming growth factor (TGF)-α family and exhibits potent neuroprotective activity. GDNF is a potent promoter of neuronal survival in the CNS and peripheral nervous system (PNS). It has a relatively high speciicity for dopaminergic neurons and thus become an efective treatment for Parkinson's diseases (PD), with clinical trials currently in progress. Protein dimers of GDNF have a reported molecular weight of 32-40 kDa(PMID: 17982417, PMID: 23251488, PMID: 11429269).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 GDNF antibody CL488-83087Download protocol
Standard Protocols
Click here to view our Standard Protocols
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