验证数据展示
产品信息
67738-1-PBS targets GOT2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig, chicken samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, rat, pig, chicken |
免疫原 | GOT2 fusion protein Ag6600 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) |
别名 | FABP 1, FABPpm, Fatty acid binding protein, FLJ40994, GOT2, KAT4, KATIV, mAspAT, mitAAT, Transaminase A |
计算分子量 | 47 kDa |
观测分子量 | 39-40 kDa |
GenBank蛋白编号 | BC000525 |
基因名称 | GOT2 |
Gene ID (NCBI) | 2806 |
RRID | AB_2918507 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P00505 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GOT2 encodes the mitochondrial glutamate oxaloacetate transaminase and plays an essential role in the intracellular NAD(H) redox balance. Upregulation of GOT2 has been reported in various cancers, including breast cancer and pancreatic cancer. GOT2 mutation leads to autosomal recessive neurometabolic disorder.