验证数据展示
产品信息
68313-1-PBS targets GTSE1 in WB, Indirect ELISA applications and shows reactivity with Human, Rat, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, Rat, mouse |
免疫原 | GTSE1 fusion protein Ag32817 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | G-2 and S-phase expressed 1 |
别名 | B99, G 2 and S phase expressed 1, GTSE 1, GTSE1, Protein B99 homolog |
计算分子量 | 77 kDa |
观测分子量 | 67 kDa |
GenBank蛋白编号 | BC006325 |
基因名称 | GTSE1 |
Gene ID (NCBI) | 51512 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q9NYZ3 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shutting it out of the nucleus and repressing its ability to induce apoptosis.