验证数据展示
产品信息
66904-1-PBS targets Glucocorticoid receptor in WB, IHC, IF-P, ELISA applications and shows reactivity with Human, mouse, rat samples.
经测试应用 | WB, IHC, IF-P, ELISA Application Description |
经测试反应性 | Human, mouse, rat |
免疫原 | Glucocorticoid receptor fusion protein Ag28431 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
别名 | GCCR, GCR, Glucocorticoid receptor, GR, GRL, NR3C1 |
计算分子量 | 86 kDa |
观测分子量 | 97 kDa |
GenBank蛋白编号 | BC015610 |
基因名称 | Glucocorticoid receptor |
Gene ID (NCBI) | 2908 |
RRID | AB_2857354 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P04150 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is a receptor for glucocorticoids, which owns a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. It is involved in cell proliferation and differentiation and specifically implicated in newborn birth weight, thus providing a biological mechanism by which NR3C1 expression may influence birth weight (PMID:22810058).