CoraLite® Plus 488-conjugated Glucocorticoid receptor Recombinant antibody
Glucocorticoid receptor Uni-rAbTM Recombinant Antibody for IF/ICC
Host / Isotype
Rabbit / IgG
Reactivity
Human, Mouse
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2F22
验证数据展示
经过测试的应用
Positive IF/ICC detected in | HepG2 cells |
Planning an IHC experiment? We recommend our IHCeasy NR3C1 Ready-To-Use IHC Kit. NR3C1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 82619-4-PBS
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-82619-4 targets Glucocorticoid receptor in IF/ICC applications and shows reactivity with Human, Mouse samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | Human, Mouse |
Immunogen | Glucocorticoid receptor fusion protein Ag21146 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
Synonyms | GCCR, GCR, Glucocorticoid receptor, GR, GRL, NR3C1 |
Calculated Molecular Weight | 86 kDa |
Observed Molecular Weight | 94-97 kDa |
GenBank Accession Number | BC015610 |
Gene Symbol | Glucocorticoid receptor |
Gene ID (NCBI) | 2908 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P04150 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is a receptor for glucocorticoids, which owns a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. It is involved in cell proliferation and differentiation and specifically implicated in newborn birth weight, thus providing a biological mechanism by which NR3C1 expression may influence birth weight (PMID:22810058).
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 Glucocorticoid receptor antibody CL488-82619-4 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |