HEXA Monoclonal antibody, PBS Only
HEXA Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, mouse, rat, rabbit
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3A4F2
验证数据展示
产品信息
60337-1-PBS targets HEXA in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | human, mouse, rat, rabbit |
| Immunogen | HEXA fusion protein Ag1854 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | hexosaminidase A (alpha polypeptide) |
| Synonyms | HEXA, Hexosaminidase subunit A, TSD |
| Calculated Molecular Weight | 529 aa, 60 kDa |
| Observed Molecular Weight | 50-54 kDa, 60-67 kDa |
| GenBank Accession Number | BC018927 |
| Gene Symbol | HEXA |
| Gene ID (NCBI) | 3073 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P06865 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Beta-hexosaminidase subunit alpha is involved in catalysis of degradation of the ganglioside GM2. Disfunction of beta-hexosaminidase leads to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. The enzyme is composed of two subunits, alpha and beta. This gene encodes alpha subunit of beta-hexosaminidase. Western blot with this antibody raised against HEXA detected 60 kDa (precursor) and 54 kDa (mature) size bands (PMID: 27682588, PMID: 30341570).
