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CoraLite® Plus 488-conjugated IFI16 Monoclonal antibody

IFI16 Monoclonal Antibody for IF/ICC

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1C10D7

Cat No : CL488-67790

Print datasheet

Synonyms

Ifi 16, IFI16, IFNGIP1, PYHIN2

验证数据展示

  • IF Staining of HeLa using CL488-67790

    IF Staining of HeLa using CL488-67790

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 IFI16 antibody (CL488-67790, Clone: 1C10D7 ) at dilution of 1:400.

经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy IFI16 Ready-To-Use IHC Kit. IFI16 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67790-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67790 targets IFI16 in IF/ICC applications and shows reactivity with Human samples.

Tested Applications IF/ICC Application Description
Tested Reactivity Human
Immunogen IFI16 fusion protein Ag30314 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name interferon, gamma-inducible protein 16
Synonyms Ifi 16, IFI16, IFNGIP1, PYHIN2
Calculated Molecular Weight 729 aa, 82 kDa
Observed Molecular Weight85-95 kDa
GenBank Accession NumberBC017059
Gene Symbol IFI16
Gene ID (NCBI) 3428
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ16666
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

IFI16 is a member of a family of interferon-inducible nuclear proteins involved in transcriptional regulation functions as a transcriptional repressor. IFI16 may be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA binding and modulating TP53 phosphorylation status. It has been reported that IFI16 participates in the regulation of autophagy, TP53-mediated cell death and innate immune response.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 IFI16 antibody CL488-67790Download protocol
Standard Protocols
Click here to view our Standard Protocols