• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

IGF2 Recombinant antibody, PBS Only

IGF2 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241746D3

Cat no : 84643-1-PBS

Print datasheet

Synonyms

proIGF-II, PP1446, Insulin-like growth factor II Ala-25 Del, IGF-II, IGF II

验证数据展示

  • WB analysis of HuH-7 using 84643-1-RR (same clone as 84643-1-PBS)

    WB analysis of HuH-7 using 84643-1-RR (same clone as 84643-1-PBS)

    HuH-7 cells were subjected to SDS PAGE followed by western blot with 84643-1-RR (IGF2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84643-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84643-1-RR

    Affinity and Kinetic Characterization of 84643-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84643-1-RR against Human IGF2 were performed. The affinity constant is 0.159 nM.

产品信息

84643-1-PBS targets IGF2 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen IGF2 fusion protein HZ-1161 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name insulin-like growth factor 2 (somatomedin A)
Synonyms proIGF-II, PP1446, Insulin-like growth factor II Ala-25 Del, IGF-II, IGF II
Observed Molecular Weight20 kDa
Gene Symbol IGF2
Gene ID (NCBI) 3481
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP01344
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Insulin-like growth factor 2 (IGF2) is a crucial protein that plays a significant role in regulating growth, particularly during normal fetal development, and is also often dysregulated during tumorigenesis. IGF2 is one of the main ligands of the type 1 IGF receptor (IGF-1R), a tyrosine kinase receptor that transmits signals upon binding with IGF-II. IGF2 is predominantly secreted via the placenta during pregnancy and, after birth, primarily by hepatocytes, with its secretion being independent of growth hormone (GH) secretion, unlike IGF-I.