CoraLite® Plus 488-conjugated IL-2 Monoclonal antibody
IL-2 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2F11C5
验证数据展示
经过测试的应用
| Positive IF-P detected in | human tonsillitis tissue |
For other applications, we recommend the unconjugated version of this antibody, 60306-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-60306 targets IL-2 in IF-P applications and shows reactivity with human samples.
| Tested Applications | IF-P Application Description |
| Tested Reactivity | human |
| Immunogen | IL-2 fusion protein Ag10199 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | interleukin 2 |
| Synonyms | Aldesleukin, IL 2, IL2, IL-2, interleukin 2, lymphokine, T cell growth factor, TCGF |
| Calculated Molecular Weight | 153 aa, 18 kDa |
| GenBank Accession Number | BC070338 |
| Gene Symbol | IL2 |
| Gene ID (NCBI) | 3558 |
| RRID | AB_2919247 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P60568 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions, including T cell proliferation, interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 IL-2 antibody CL488-60306 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |