CoraLite®594-conjugated IL-2 Monoclonal antibody
IL-2 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
IF-P
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
2F11C5
验证数据展示
经过测试的应用
Positive IF-P detected in | human tonsillitis tissue |
For other applications, we recommend the unconjugated version of this antibody, 60306-1-Ig
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-60306 targets IL-2 in IF-P applications and shows reactivity with human samples.
Tested Applications | IF-P Application Description |
Tested Reactivity | human |
Immunogen | IL-2 fusion protein Ag10199 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | interleukin 2 |
Synonyms | Aldesleukin, IL 2, IL2, IL-2, interleukin 2, lymphokine, T cell growth factor, TCGF |
Calculated Molecular Weight | 153 aa, 18 kDa |
GenBank Accession Number | BC070338 |
Gene Symbol | IL2 |
Gene ID (NCBI) | 3558 |
RRID | AB_2919916 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P60568 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions, including T cell proliferation, interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
实验方案
Product Specific Protocols | |
---|---|
IF protocol for CL594 IL-2 antibody CL594-60306 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |