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Anti-Human IL-2RG/CD132 Rabbit Recombinant Antibody, PBS Only

IL-2RG/CD132 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

242020H6

Cat no : 98234-1-PBS

Print datasheet

Synonyms

IL2RG, IL 2RG, IL 2R subunit gamma, IL 2 receptor subunit gamma, gammaC

验证数据展示

  • FC experiment of human PBMCs using 98234-1-RR (same clone as 98234-1-PBS)

    FC experiment of human PBMCs using 98234-1-RR (same clone as 98234-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human IL-2RG/CD132 Rabbit Recombinant Antibody (98234-1-RR, Clone: 242020H6), or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD4. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98234-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98234-1-RR (same clone as 98234-1-PBS)

    FC experiment of human PBMCs using 98234-1-RR (same clone as 98234-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human IL-2RG/CD132 Rabbit Recombinant Antibody (98234-1-RR, Clone: 242020H6)(red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98234-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98234-1-RR

    Affinity and Kinetic Characterization of 98234-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98234-1-RR against Human IL-2RG/CD132 were performed. The affinity constant is 1.55 nM.

产品信息

98234-1-PBS targets IL-2RG/CD132 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name interleukin 2 receptor, gamma (severe combined immunodeficiency)
Synonyms IL2RG, IL 2RG, IL 2R subunit gamma, IL 2 receptor subunit gamma, gammaC
Calculated Molecular WeightNM_000206.3
GenBank Accession NumberNM_000206.3
Gene Symbol IL2RG
Gene ID (NCBI) 3561
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP31785-1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The interleukin-2 receptor (IL-2R) is a heterotrimeric receptor consisting of three subunits, alpha (IL-2RA), beta (IL-2RB), and gamma (IL-2RG). IL-2RG, also known as CD132, is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in the gene of IL-2RG cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.