CoraLite® Plus 488-conjugated IL-4 Monoclonal antibody
IL-4 Monoclonal Antibody for
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1G2C5
验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 66142-1-Ig
产品信息
CL488-66142 targets IL-4 in applications and shows reactivity with human samples.
| Tested Applications | Application Description |
| Tested Reactivity | human |
| Immunogen | IL-4 fusion protein Ag9940 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | interleukin 4 |
| Synonyms | B cell stimulatory factor 1, Binetrakin, BSF 1, BSF1, IL 4, IL4, IL-4, interleukin 4, Pitrakinra, PS1TP5BP1 |
| Calculated Molecular Weight | 153 aa, 17 kDa |
| Observed Molecular Weight | 18 kDa |
| GenBank Accession Number | BC070123 |
| Gene Symbol | IL-4 |
| Gene ID (NCBI) | 3565 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P05112 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.
