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Inhibin Beta A Polyclonal antibody

Inhibin Beta A Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

ELISA and More (3)

Conjugate

Unconjugated

Cat no : 10651-1-AP

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Synonyms

INHBA, Inhibinβ-A, inhibin, beta A, Inhibin β-A, EDF



产品信息

10651-1-AP targets Inhibin Beta A in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Applications ELISA Application Description
Cited ApplicationsWB, IHC, IF
Tested Reactivity human
Cited Reactivityhuman, mouse, sheep
Immunogen Inhibin Beta A fusion protein Ag1001 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name inhibin, beta A
Synonyms INHBA, Inhibinβ-A, inhibin, beta A, Inhibin β-A, EDF
Calculated Molecular Weight 47 kDa
Observed Molecular Weight42 kDa
GenBank Accession NumberBC007858
Gene Symbol Inhibin beta A
Gene ID (NCBI) 3624
RRIDAB_2125851
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP08476
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Inhibin is a 32-kD dimeric glycoprotein consisting of an alpha subunit and one of two beta subunits (beta A or beta B) leading to inhibin A or B, respectively, which was isolated and cloned on the basis of its ability to inhibit FSH release from the pituitary. Inhibin beta A forms a disulfide-linked homo-dimer known as activin A, which has been implicated in multiple biologic processes, including neoplastic progression. The inhibin beta A can also bind the beta B and A isoforms to form activin AB and inhibin, respectively.

发表文章

SpeciesApplicationTitle
humanIF

Nat Commun

Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.

Authors - Yi-Ing Chen

Development

Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination.

Authors - Dipankar J Dutta
mouseWB

PLoS One

Action mechanism of inhibin α-subunit on the development of Sertoli cells and first wave of spermatogenesis in mice.

Authors - Cai Kailai K
humanIHC,IF

Transl Oncol

Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer

Authors - Nanxin Zheng

Hepatol Commun

Activin A is a prominent autocrine regulator of hepatocyte growth arrest.

Authors - Srividyameena Haridoss

BMC Cancer

Esophageal squamous cell carcinoma invasion is inhibited by Activin A in ACVRIB-positive cells.

Authors - Holli A Loomans