验证数据展示
产品信息
67668-1-PBS targets Ins1 in IHC, IF-P, Indirect ELISA applications and shows reactivity with mouse, rat samples.
经测试应用 | IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | mouse, rat |
免疫原 | Ins1 fusion protein Ag29988 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | insulin I |
别名 | Insulin, insulin1, insulin I, Ins2 rs1, Ins-1 |
计算分子量 | 12 kDa |
GenBank蛋白编号 | NM_008386 |
基因名称 | Ins1 |
Gene ID (NCBI) | 16333 |
RRID | AB_2882864 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P01325 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
insulin I is a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked heterodimeric functional protein that is stored in secretory granules. An increase in blood glucose levels, among others, induces the release of insulin from the secretory granules. Mice deficient in the functional hormone encoded by this gene develop diabetes mellitus.