验证数据展示
产品信息
67668-1-PBS targets Ins1 in IHC, IF-P, Indirect ELISA applications and shows reactivity with mouse, rat samples.
Tested Applications | IHC, IF-P, Indirect ELISA Application Description |
Tested Reactivity | mouse, rat |
Immunogen | Ins1 fusion protein Ag29988 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | insulin I |
Synonyms | Insulin, insulin1, insulin I, Ins2 rs1, Ins-1 |
Calculated Molecular Weight | 12 kDa |
GenBank Accession Number | NM_008386 |
Gene Symbol | Ins1 |
Gene ID (NCBI) | 16333 |
RRID | AB_2882864 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P01325 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
insulin I is a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked heterodimeric functional protein that is stored in secretory granules. An increase in blood glucose levels, among others, induces the release of insulin from the secretory granules. Mice deficient in the functional hormone encoded by this gene develop diabetes mellitus.