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  • Featured Product
  • KD/KO Validated

Jagged1 Monoclonal antibody, PBS Only

Jagged1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgA

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2A7D11

Cat No : 66890-1-PBS

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Synonyms

AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1

验证数据展示

  • WB analysis of HEK-293 using 66890-1-Ig (same clone as 66890-1-PBS)

    WB analysis of HEK-293 using 66890-1-Ig (same clone as 66890-1-PBS)

    WB result of Jagged1 antibody (66890-1-Ig; 1:12000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Jagged1 transfected HEK-293 cells. This data was developed using the same antibody clone with 66890-1-PBS in a different storage buffer formulation.

产品信息

66890-1-PBS targets Jagged1 in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human
Immunogen Jagged1 fusion protein Ag11891 种属同源性预测
Host / Isotype Mouse / IgA
Class Monoclonal
Type Antibody
Full Name jagged 1 (Alagille syndrome)
Synonyms AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1
Calculated Molecular Weight 1218 aa, 134 kDa
Observed Molecular Weight 150 kDa
GenBank Accession NumberBC098393
Gene Symbol Jagged1
Gene ID (NCBI) 182
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP78504
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653).