验证数据展示
产品信息
66890-1-PBS targets Jagged1 in WB, ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | Human |
免疫原 | Jagged1 fusion protein Ag11891 种属同源性预测 |
宿主/亚型 | Mouse / IgA |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | jagged 1 (Alagille syndrome) |
别名 | AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1 |
计算分子量 | 1218 aa, 134 kDa |
观测分子量 | 150 kDa |
GenBank蛋白编号 | BC098393 |
基因名称 | Jagged1 |
Gene ID (NCBI) | 182 |
RRID | AB_2882220 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P78504 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653).